EM

Ellie McGuire

VC

Managing Partner, Polaris Partners

Academic biotech spinout specialist and innovator

Boston, MA$300K–$2M checks3 notable investments
Pre-SeedSeedSeries A
BioHealthcareConsumer

Background

Ellie McGuire is a Managing Partner at Polaris Partners in the Boston office and co-founder of the Polaris Innovation Fund, which invests in early-stage academic biomedical research. She previously was Head of Business Development at Lyndra, and held leadership and consulting roles at Arsia Therapeutics, SQZ Biotechnologies, and XTuit Pharmaceuticals. She is an Expert in Residence for the Harvard Office of Technology Development. She serves on boards of Muna Therapeutics, Montis Biosciences, FOLX Health, and Noema Pharma.

Investment Thesis

Early-stage biotech companies spun from academic medical centers with the potential to translate breakthrough science into medicines.

Investment Focus

Stages

Pre-SeedSeedSeries A

Typical check: $300K–$2M

Sectors

BioHealthcareConsumer

Based in: Boston, MA (North America)

Notable Investments

Last updated: Jun 11, 2026